The prevalence and risk factors for subjective cognitive decline (SCD) and its correlation with objective cognition decline (OCD) among community-dwelling older adults is inconsistent.
Older adults underwent neuropsychological and clinical evaluations to reach a consensus on diagnoses.
This study included 7486 adults without mild cognitive impairment and dementia (mean age: 71.35 years [standard deviation = 5.40]). The sex-, age-, and residence-adjusted SCD prevalence was 58.33% overall (95% confidence interval: 58.29% to 58.37%), with higher rates of 61.25% and 59.87% in rural and female subgroups, respectively. SCD global and OCD language, SCD memory and OCD global, SCD and OCD memory, and SCD and OCD language were negatively correlated in fully adjusted models. Seven health and lifestyle factors were associated with an increased risk for SCD.
SCD affected 58.33% of older adults and may indicate concurrent OCD, which should prompt the initiation of preventative intervention for dementia.

SCD affects 58.33% of older adults in China.
SCD may indicate concurrent objective cognitive decline.
Difficulty finding words and memory impairments may indicate a risk for AD.
The presence of SCD may prompt preventative treatment initiation of MCI or dementia.
Social network factors may be initial targets for the early prevention of SCD.

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This post is Copyright: Gui‐Rong Cheng,
Dan Liu,
Lin‐Ya Huang,
Gang‐Bin Han,
Fei‐Fei Hu,
Zhao‐Xia Wu,
Xiao‐Ming He,
Yu‐Wei Huang,
Ya‐Fu Yu,
Lang Xu,
Jin‐Quan Li,
Yu‐Shan Chen,
Zhen Wei,
Qiong Wu,
Yu‐Fei Mei,
Xing‐Xing Chen,
Yang‐Ming Ou,
Jing‐Jing Zhang,
Meng‐Liu Yang,
Peng‐Fei Lian,
Wei Tan,
Xin‐Yan Xie,
Yan Zeng | November 15, 2023

Wiley: Alzheimer’s & Dementia: Table of Contents