Nature Neuroscience, Published online: 16 November 2023; doi:10.1038/s41593-023-01484-4This study by Zielinski et al. used cryo-EM to compare Aβ fibril structures from mouse models to those from patients with Alzheimer’s disease. It revealed that tg-APPArcSwe mice exhibit fibrils resembling those predominantly found in sporadic Alzheimer’s disease cases.
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This post is Copyright: Mara Zielinski | November 16, 2023