Nature Neuroscience, Published online: 14 September 2023; doi:10.1038/s41593-023-01436-ySu et al. show that loss of GluN2A in adult mice is sufficient to elicit antidepressant-like responses without evoking psychomimetic effects, and that GluN2A is necessary for ketamine and MK-801 to induce rapid antidepressant-like effects.

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This post is Copyright: Tonghui Su | September 14, 2023
Nature Neuroscience