Nature Neuroscience, Published online: 20 November 2023; doi:10.1038/s41593-023-01494-2Wang et al. showed that genetic disruption of TFEB and v-ATPase-mediated lysosomal signaling leads to increased tau pathology but defective microglia activation, demonstrating an essential role of the lysosome in regulating microglia activity.
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This post is Copyright: Baiping Wang | November 20, 2023