Rastermap: a discovery method for neural population recordings

by Clinical Neuropsychologist | Wednesday, October 16, 2024 | Neuroscience

Nature Neuroscience, Published online: 16 October 2024; doi:10.1038/s41593-024-01783-4Rastermap is an analysis method for exploring dynamical and spatial relationships among hundreds to hundreds of thousands of neurons. The algorithm uses a fast optimization technique...

Integrating brainstem and cortical functional architectures

by Clinical Neuropsychologist | Wednesday, October 16, 2024 | Neuroscience

Nature Neuroscience, Published online: 16 October 2024; doi:10.1038/s41593-024-01787-0Hansen et al. used in vivo functional imaging of the human brainstem and cortex to demonstrate how the brainstem shapes cortical functional architecture, including oscillatory...

The hippocampal CA2 region discriminates social threat from social safety

by Clinical Neuropsychologist | Tuesday, October 15, 2024 | Neuroscience

Nature Neuroscience, Published online: 15 October 2024; doi:10.1038/s41593-024-01771-8The hippocampal dorsal CA2 enables the recognition of novel conspecifics. Kassraian et al. show that it is also required for discriminating safety- versus threat-associated...

A cross-disease resource of living human microglia identifies disease-enriched subsets and tool compounds recapitulating microglial states

by Clinical Neuropsychologist | Tuesday, October 15, 2024 | Neuroscience

Nature Neuroscience, Published online: 15 October 2024; doi:10.1038/s41593-024-01764-7Profiling >200,000 live human microglia from 74 donors across neurological diseases reveals 12 subtypes of microglia that were validated in situ. Camptothecin is also identified...

Integrated multimodal cell atlas of Alzheimer’s disease

by Clinical Neuropsychologist | Monday, October 14, 2024 | Neuroscience

Nature Neuroscience, Published online: 14 October 2024; doi:10.1038/s41593-024-01774-5The affected cellular populations during Alzheimer’s disease progression remain understudied. Here the authors use a cohort of 84 donors, quantitative neuropathology and multimodal...

Perioperative and postoperative effects of hydrostatic pressure applied to the dura mater on central nervous system in unilateral biportal endoscopic spine surgery

by Clinical Neuropsychologist | Tuesday, October 8, 2024 | Neuroscience

Objectives: To evaluate the changes in optic nerve sheath diameter (ONSD) caused by this pressure applied to the dura mater and postoperative complications. Methods: The study was conducted between 01.01.2022 and 01.06.2022 at Private Medicabil Hospital. The ONSD was...