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Dementia Subtypes for Differential Diagnosis


Cortical Dementias #

Alzheimer’s Disease Dementia #

  • Amnestic variant
  • Posterior cortical atrophy / Posterior variant (PCA)
  • Logopenic variant primary progressive aphasia (lvPPA) (Atypical Alzheimer’s)

Frontotemporal Dementia (FTD) #

Language Variant #

  • Primary progressive aphasia (PPA)
    • Semantic variant primary progressive aphasia (svPPA)
    • Nonfluent agrammatic primary progressive aphasia (nfaPPA)

Behavioural Variant #

  • Behavioural variant fronto-temporal dementia (bvFTD)

Subcortical Dementias #

  • Huntington’s disease dementia
  • Vascular disease dementia
  • Parkinson’s disease dementia

Atypical Parkinsonian Syndromes #

  • Progressive supra-nuclear palsy (PSP)
  • Multiple system atrophy (MSA)

Cortico-subcortical Dementias #

  • Corticobasal degeneration (CBD)
  • Creutzfeldt-Jakob disease dementia
  • Dementia with Lewy Bodies (DLB)

Other differential diagnoses #

  • Accelerated long-term forgetting
  • Delirium
  • Mild Cognitive Impairment (temporary or prodromal to a dementia syndrome)
  • Cognitive impairment due to:
    • alcohol toxicity
    • anaesthesia
    • genetic and developmental disorders
    • hydrocephalus
    • multiple sclerosis
    • stroke
    • traumatic brain injury
    • pharmacotherapies
    • radiation treatment
    • surgery
    • toxic chemicals
    • and more!
Cognitive Impairment, Dementia, Differential Diagnosis, Neuropsychological Assessment
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