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A neuron–glia lipid metabolic cycle couples daily sleep to mitochondrial homeostasis

by Clinical Neuropsychologist Online | Thursday, February 15, 2024 | Neuroscience

Nature Neuroscience, Published online: 15 February 2024; doi:10.1038/s41593-023-01568-1Haynes et al. report a daily, sleep-dependent neuron–glia lipid metabolic cycle. ApoE-dependent lipid transfer from neurons to glia protects neurons from oxidative damage during...

A unifying theory explains seemingly contradictory biases in perceptual estimation

by Clinical Neuropsychologist Online | Thursday, February 15, 2024 | Neuroscience

Nature Neuroscience, Published online: 15 February 2024; doi:10.1038/s41593-024-01574-xDespite a long history of studying perceptual biases in neuroscience, many of the biases remain difficult to explain and even appear to be contradictory. The authors propose a...

Increased Interhemispheric Connectivity of a Distinct Type of Hippocampal Pyramidal Cells

by Clinical Neuropsychologist Online | Thursday, February 15, 2024 | Neuroscience

Neurons typically generate action potentials at their axon initial segment based on the integration of synaptic inputs. In many neurons, the axon extends from the soma, equally weighting dendritic inputs. A notable exception is found in a subset of hippocampal...

Spatiotemporal Correlation between Amyloid and Tau Accumulations Underlies Cognitive Changes in Aging

by Clinical Neuropsychologist Online | Thursday, February 15, 2024 | Neuroscience

It is poorly known how Aβ and tau accumulations associate at the spatiotemporal level in the in vivo human brain to impact cognitive changes in older adults prior to AD symptoms onset. In this study, we used a graph theory-based spatiotemporal analysis to characterize...

Visual Stimuli Modulate Local Field Potentials But Drive No High-Frequency Activity in Human Auditory Cortex

by Clinical Neuropsychologist Online | Thursday, February 15, 2024 | Neuroscience

Neuroimaging studies suggest cross-sensory visual influences in human auditory cortices (ACs). Whether these influences reflect active visual processing in human ACs, which drives neuronal firing and concurrent broadband high-frequency activity (BHFA; >70 Hz), or...
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