by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION We investigated whether retinal capillary perfusion is a biomarker of cerebral small vessel disease and impaired cognition among Black Americans, an understudied group at higher risk for dementia. METHODS We enrolled 96 Black Americans without...
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION The results of the CLARITY-AD, GRADUATE I and II, and TRAILBLAZER-ALZ 2 trials have rekindled discussion on the impact of amyloid-targeting drugs. We use a Bayesian approach to quantify how rational observers would have updated their prior...
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION Verbal fluency tasks are common in Alzheimer’s disease (AD) assessments. Yet, standard valid response counts fail to reveal disease-specific semantic memory patterns. Here, we leveraged automated word-property analysis to capture...
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Neuroscience
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by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Neuroscience
Direct human brain recordings have confirmed the presence of high-frequency oscillatory events, termed ripples, during awake behavior. While many prior studies have focused on medial temporal lobe (MTL) ripples during memory retrieval, here we investigate ripples...
