by Clinical Neuropsychologist Online | Wednesday, May 8, 2024 | Dementia
Abstract INTRODUCTION Cerebrovascular dysfunction is a pathological hallmark of Alzheimer’s disease (AD). Nevertheless, detecting cerebrovascular changes within bulk tissues has limited our ability to characterize proteomic alterations from less abundant cell...
by Clinical Neuropsychologist Online | Wednesday, May 8, 2024 | Dementia
Abstract BACKGROUND Alzheimer’s disease (AD) is the most common cause of dementia worldwide, with apolipoprotein Eε4 (APOEε4) being the strongest genetic risk factor. Current clinical diagnostic imaging focuses on amyloid and tau; however, new methods are needed...
by Clinical Neuropsychologist Online | Wednesday, May 8, 2024 | Dementia
Abstract INTRODUCTION Platelets serve as the primary peripheral reservoir of amyloid beta (Aβ). However, there is limited research on platelet markers in routine blood examinations, particularly with regard to the large platelet ratio (P-LCR) in Alzheimer’s...
by Clinical Neuropsychologist Online | Tuesday, May 7, 2024 | Neurorehabilitation
Neurorehabilitation and Neural Repair, Ahead of Print. BackgroundRecent evidence demonstrates that manually triggered vagus nerve stimulation (VNS) combined with rehabilitation leads to increased recovery of upper limb motor function after stroke. This approach is...
by Clinical Neuropsychologist Online | Tuesday, May 7, 2024 | Dementia
Dementia, Volume 23, Issue 5, Page 757-778, July 2024. Hope is an important but overlooked phenomenon in dementia studies. Few studies have examined how people with dementia experience or perceive hope, possibly because it is seen as a diagnosis without hope. In this...