by Clinical Neuropsychologist Online | Thursday, July 4, 2024 | Neuroscience
Nature Neuroscience, Published online: 04 July 2024; doi:10.1038/s41593-024-01694-4Bonnavion, Varin and colleagues show that striatal projection neurons that coexpress dopamine D1 and D2 receptors have unique physiological properties and serve as a crucial third...
by Clinical Neuropsychologist Online | Thursday, July 4, 2024 | Dementia
Abstract INTRODUCTION Although poor glycemic control is associated with dementia, it is unknown if variability in glycemic control, even in those with optimal glycosylated hemoglobin A1c (HbA1c) levels, increases dementia risk. METHODS Among 171,964 people with type 2...
by Clinical Neuropsychologist Online | Thursday, July 4, 2024 | Neuroscience
Phospholipids (PLs) are asymmetrically distributed at the plasma membrane. This asymmetric lipid distribution is transiently altered during calcium-regulated exocytosis, but the impact of this transient remodeling on presynaptic function is currently unknown. As...
by Clinical Neuropsychologist Online | Wednesday, July 3, 2024 | Dementia
Abstract INTRODUCTION Accurate testing for Alzheimer’s disease (AD) represents a crucial step for therapeutic advancement. Currently, tests are expensive and require invasive sampling or radiation exposure. METHODS We developed a nanoscale flow cytometry...
by Clinical Neuropsychologist Online | Wednesday, July 3, 2024 | Dementia
Abstract The Dominantly Inherited Alzheimer Network (DIAN) initially was funded by the National Institute on Aging (NIA) in 2008 and thus was able to adopt and incorporate the protocols developed by the Alzheimer’s Disease Neuroimaging Initiative (ADNI) that had...
