by Clinical Neuropsychologist Online | Monday, August 5, 2024 | Dementia
Abstract INTRODUCTION We investigated the link between habitual caffeine intake with memory impairments and cerebrospinal fluid (CSF) biomarkers in mild cognitive impairment (MCI) and Alzheimer’s disease (AD) patients. METHODS MCI (N = 147) and AD (N = 116)...
by Clinical Neuropsychologist Online | Monday, August 5, 2024 | Dementia
Abstract INTRODUCTION The Health and Retirement Study International Partner Surveys (HRS IPS) have rich longitudinal data, but the brevity of cognitive batteries is a limitation. METHODS We used data from a substudy of the English Longitudinal Study of Ageing (ELSA)...
by Clinical Neuropsychologist Online | Monday, August 5, 2024 | Neuroscience
Nature Neuroscience, Published online: 05 August 2024; doi:10.1038/s41593-024-01728-xNeuronal activity contributes to synapse formation and plasticity. Here the authors demonstrate that activity stimulates developmental programs to directly modulate synapse formation....
by Clinical Neuropsychologist Online | Monday, August 5, 2024 | Neuroscience
Nature Neuroscience, Published online: 05 August 2024; doi:10.1038/s41593-024-01730-3In Alzheimer’s disease, neurons are considered the sole source of amyloid-β (Aβ) peptides that form plaques. Here the authors show that oligodendrocytes, the myelinating glial cells...
by Clinical Neuropsychologist Online | Monday, August 5, 2024 | Neuroscience
Nature Neuroscience, Published online: 05 August 2024; doi:10.1038/s41593-024-01726-zAstrocyte diversity is greatly influenced by local environmental modulation. Wang et al. report a critical role for astrocytic primary cilia in transmitting local cues that drive the...