by Clinical Neuropsychologist Online | Thursday, August 29, 2024 | Neuroscience
The anterior cingulate cortex (ACC) is a key cortical region for pain perception and emotion. Different forms of synaptic plasticity, including long-term potentiation (LTP) and long-term depression (LTD), have been reported in the ACC. Synaptic tagging of LTP plays an...
by Clinical Neuropsychologist Online | Wednesday, August 28, 2024 | Dementia
Abstract INTRODUCTION We investigated blood DNA methylation patterns associated with 15 well-established cerebrospinal fluid (CSF) biomarkers of Alzheimer’s disease (AD) pathophysiology, neuroinflammation, and neurodegeneration. METHODS We assessed DNA...
by Clinical Neuropsychologist Online | Wednesday, August 28, 2024 | Dementia
Abstract INTRODUCTION The established link between DNA methylation and pathophysiology of dementia, along with its potential role as a molecular mediator of lifestyle and environmental influences, positions blood-derived DNA methylation as a promising tool for early...
by Clinical Neuropsychologist Online | Wednesday, August 28, 2024 | Dementia
Abstract INTRODUCTION Typical Alzheimer’s disease (AD) and limbic-predominant age-related TAR DNA-binding protein 43 (TDP-43) encephalopathy (LATE) are two neurodegenerative diseases that present with a similar initial amnestic clinical phenotype but are...
by Clinical Neuropsychologist Online | Wednesday, August 28, 2024 | Dementia
Abstract INTRODUCTION The role of information processing speed (IPS) on relationships between episodic memory (EM) and central remodeling features in amnestic mild cognitive impairment (aMCI) was investigated. METHODS Neuropsychological evaluations and multimodal...
