by Clinical Neuropsychologist Online | Friday, August 23, 2024 | Dementia
Abstract INTRODUCTION The in vivo detection of mixed Alzheimer’s disease (AD) and α-synuclein (αSyn) pathology is important for clinical management and prognostic stratification. We investigated the contribution of αSyn pathology, detected by cerebrospinal fluid...
by Clinical Neuropsychologist Online | Friday, August 23, 2024 | Dementia
Abstract INTRODUCTION We aimed to assess the impact of cholinesterase inhibitors (ChEIs) and memantine on cognition, major adverse cardiovascular events (MACE) and mortality in dementia with Lewy bodies (DLB). METHODS A total of 1,095 incident DLB patients from the...
by Clinical Neuropsychologist Online | Friday, August 23, 2024 | Dementia
Abstract INTRODUCTION The paramagnetic iron, diamagnetic amyloid beta (Aβ) plaques and their interaction are crucial in Alzheimer’s disease (AD) pathogenesis, complicating non-invasive magnetic resonance imaging for prodromal AD detection. METHODS We used a...
by Clinical Neuropsychologist Online | Friday, August 23, 2024 | Dementia
Abstract INTRODUCTION We used clinical assessment records to provide pan-Canadian estimates of the prevalence and risks associated with recent (within the last 3 days) critical wandering among home care clients, with and without dementia. METHODS The data source is...
by Clinical Neuropsychologist Online | Friday, August 23, 2024 | Neuroscience
Nature Neuroscience, Published online: 23 August 2024; doi:10.1038/s41593-024-01723-2What follows is not a detailed biography of Jim Simons, whose diversity of talents and activities as a mathematician, educator, administrator, life scientist, philanthropist and...