by Clinical Neuropsychologist Online | Tuesday, September 24, 2024 | Neuroscience
Nature Neuroscience, Published online: 24 September 2024; doi:10.1038/s41593-024-01772-7Siddiqi et al. identified lesion locations that reduced probability of PTSD. These were connected to a brain circuit in which increased connectivity was associated with PTSD, thus...
by Clinical Neuropsychologist Online | Tuesday, September 24, 2024 | Neuroscience
Nature Neuroscience, Published online: 24 September 2024; doi:10.1038/s41593-024-01768-3The authors perform the first single-cell profiling of m6A in the mouse brain. They uncover relative hypomethylation of microglial mRNA compared to other cell types, and they...
by Clinical Neuropsychologist Online | Monday, September 23, 2024 | Dementia
Abstract INTRODUCTION We examined the burden of Alzheimer’s disease and other dementias (ADOD) and attributable factors at the national and provincial levels in China. METHODS Using the Global Burden of Diseases Study 2021, we estimated incidence, prevalence,...
by Clinical Neuropsychologist Online | Monday, September 23, 2024 | Dementia
Abstract INTRODUCTION Subjective cognitive decline (SCD) may be an early marker of Alzheimer’s disease (AD) pathology. Until recently, it was impossible to measure biomarkers specific for α-synuclein pathology; therefore, its association with subjective reports...
by Clinical Neuropsychologist Online | Monday, September 23, 2024 | Dementia
Abstract Early diagnosis is crucial to treatment success. This is especially relevant for Alzheimer’s disease (AD), with its protracted preclinical phase. Most health care systems do not have the resources to conduct large-scale AD screenings in middle-aged...