by Clinical Neuropsychologist Online | Wednesday, November 27, 2024 | Neuroscience
Nature Neuroscience, Published online: 27 November 2024; doi:10.1038/s41593-024-01800-6Individuals with autism spectrum disorder show neural patterns different from those of neurotypical individuals. Here the authors show that this variation reflects a computational...
by Clinical Neuropsychologist Online | Tuesday, November 26, 2024 | Dementia
Abstract INTRODUCTION Non-pharmacological interventions may offer significant benefits to the quality of life for persons with primary progressive aphasia (PPA) and their care partners but have lacked efficacy trials. To help fill the efficacy gap, we provide the...
by Clinical Neuropsychologist Online | Tuesday, November 26, 2024 | Dementia
Abstract INTRODUCTION Alterations in locus coeruleus’ (LC) metabolic turnover are associated with Alzheimer’s disease (AD)-pathology and cognitive impairment. However, the evolution of these changes across disease stages and their functional relevance remains...
by Clinical Neuropsychologist Online | Tuesday, November 26, 2024 | Dementia
Abstract The presence of multiple pathologies is the largest predictor of dementia. A major gap in the field is the in vivo detection of mixed pathologies and their antecedents. The Alzheimer’s Disease Research Centers (ADRCs) are uniquely positioned to address...
by Clinical Neuropsychologist Online | Tuesday, November 26, 2024 | Dementia
Abstract INTRODUCTION Alzheimer’s disease (AD) is a highly heritable disease (60%–80%). Amyloid beta (Aβ) 42/40, neurofilament light chain (NfL), and glial fibrillary acidic protein (GFAP) are plasma biomarkers for AD. Clinical biomarker research would be served...
