by Clinical Neuropsychologist Online | Thursday, November 21, 2024 | Dementia
Abstract BACKGROUND Peak-width of skeletonized mean diffusivity (PSMD), a neuroimaging marker of cerebral small vessel disease (SVD), has shown excellent instrumental properties. Here, we extend our work to perform a biological validation of PSMD. METHODS We included...
by Clinical Neuropsychologist Online | Thursday, November 21, 2024 | Neuro Podcasts
Would you rather read the transcript? Click here. I talk to a lot of folks during my consulting meetings and coaching groups who are interested in offering an evaluation “menu” in their testing practices. Typically this takes the form of “brief” evaluations answering...
by Clinical Neuropsychologist Online | Thursday, November 21, 2024 | Neuroscience
Nature Neuroscience, Published online: 21 November 2024; doi:10.1038/s41593-024-01722-3The cerebral cortex shows complex organization across diverse biological scales, from regional chemical and cellular specializations to macroscale functional networks. Zhang et al....
by Clinical Neuropsychologist Online | Thursday, November 21, 2024 | Neuroscience
Nature Neuroscience, Published online: 21 November 2024; doi:10.1038/s41593-024-01801-5Using cryo-electron tomography (cryo-ET) and proteomics, this study identifies the tethering of pathological tau filaments within defined brain extracellular vesicles in Alzheimer’s...
by Clinical Neuropsychologist Online | Thursday, November 21, 2024 | Neuroscience
Nature Neuroscience, Published online: 21 November 2024; doi:10.1038/s41593-024-01812-2Here Zhang et al. establish multiscale relationships that link postmortem cell-type distributions with the in vivo functional organization of the human cerebral cortex, as assessed...
