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Time to align sensitive cognitive assessment with protein biomarkers in Alzheimer’s disease

by Clinical Neuropsychologist Online | Monday, January 20, 2025 | Neuropsychology (general)

Journal of Neuropsychology, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: Jet M. J. Vonk | January 20, 2025 Wiley: Journal of Neuropsychology:...

Mapping the cellular etiology of schizophrenia and complex brain phenotypes

by Clinical Neuropsychologist Online | Monday, January 20, 2025 | Neuroscience

Nature Neuroscience, Published online: 20 January 2025; doi:10.1038/s41593-024-01834-wDuncan and colleagues link specific human brain cell types to schizophrenia and other complex brain phenotypes, providing mechanistic insights and a cellular taxonomy for psychiatric...

White matter hyperintensities and TDP‐43 pathology in Alzheimer’s disease

by Clinical Neuropsychologist Online | Friday, January 17, 2025 | Dementia

Abstract INTRODUCTION Greater white matter hyperintensities (WMHs) on magnetic resonance imaging (MRI) are seen with transactive response DNA-binding protein 43 (TDP-43) pathology in frontotemporal lobar degeneration (FTLD-TDP). WMH associations with TDP-43 pathology...

Usage patterns of cognitive assessments during Medicare’s Annual Wellness Visit: A national survey

by Clinical Neuropsychologist Online | Friday, January 17, 2025 | Dementia

Abstract INTRODUCTION Medicare’s Annual Wellness Visit (AWV) is a logical opportunity for early detection of cognitive impairment, but recent data for uptake and cognitive assessments during it are lacking. METHODS We surveyed Medicare beneficiaries of a...

Long‐range inputome of prefrontal GABAergic interneurons in the Alzheimer’s disease mouse

by Clinical Neuropsychologist Online | Friday, January 17, 2025 | Dementia

Abstract INTRODUCTION Alzheimer’s disease (AD) is the most common neurodegenerative disease, characterized by damage to cortical circuits. However, the mechanisms underlying AD-associated changes in long-range circuits remain poorly understood. METHODS In this...
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