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Differential roles of Alzheimer’s disease plasma biomarkers in stepwise biomarker‐guided diagnostics

by Clinical Neuropsychologist Online | Wednesday, February 5, 2025 | Dementia

Abstract INTRODUCTION This study aimed to investigate the differential roles of various plasma biomarkers in a stepwise diagnostic strategy for Alzheimer’s disease (AD). METHODS A total of 2984 participants, including 666 cognitively unimpaired (CU), 2032 with...

Resting‐State Functional MRI Regional Homogeneity Correlates With Motor Scores in Parkinson’s Disease

by Clinical Neuropsychologist Online | Tuesday, February 4, 2025 | Neuroimaging

ABSTRACT Background and Purpose This study investigated the neural mechanisms underlying Parkinson’s disease (PD) subtypes—tremor dominant (TD) and postural instability gait difficulty (PIGD)—by analyzing regional homogeneity (ReHo) values from resting-state...

Factors Associated With Silent Brain Infarcts After Middle Cerebral Artery Stenting or Balloon Angioplasty

by Clinical Neuropsychologist Online | Tuesday, February 4, 2025 | Neuroimaging

ABSTRACT Background and Purpose Silent brain infarcts (SBIs), which manifest as dot-like lesions on diffusion-weighted imaging (DWI) after endovascular procedures, are associated with an increased risk of stroke, dementia, and cognitive decline. We aimed to identify...

Separating cognitive and motor processes in the behaving mouse

by Clinical Neuropsychologist Online | Tuesday, February 4, 2025 | Neuroscience

Nature Neuroscience, Published online: 04 February 2025; doi:10.1038/s41593-024-01859-1Using a novel method for isolating cognitive and motor neural dynamics, the authors show that dynamics often attributed to cognitive processes were corrupted by movements and that...

The developmental emergence of reliable cortical representations

by Clinical Neuropsychologist Online | Tuesday, February 4, 2025 | Neuroscience

Nature Neuroscience, Published online: 04 February 2025; doi:10.1038/s41593-024-01857-3Sensory experience transforms endogenously structured cortical networks with diverse and unreliable visual responses into reliable representations. This process is proposed to...
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