by Clinical Neuropsychologist Online | Wednesday, March 5, 2025 | Dementia
Abstract INTRODUCTION High levels of chronic stress and low social support have been associated with worse cognition among older adults, but the underlying mechanisms remain unclear. METHODS We included 2117 older adults (mean age 65.5 years) enrolled in the Health...
by Clinical Neuropsychologist Online | Wednesday, March 5, 2025 | Dementia
Abstract INTRODUCTION We systematically characterized plasma protein profiles in cerebral amyloid angiopathy (CAA) using proteomics and identified a hub protein panel for disease diagnosis and risk stratification. METHODS A total of 146 patients with probable CAA and...
by Clinical Neuropsychologist Online | Wednesday, March 5, 2025 | Dementia
Abstract BACKGROUND Heterogeneity in Alzheimer’s disease (AD) progression introduces variability in treatment effect assessments. Using predicted future progression as an AD prognostic covariate (APC) may reduce this variability. This study evaluates this...
by Clinical Neuropsychologist Online | Wednesday, March 5, 2025 | Dementia
Abstract INTRODUCTION The progressive nature of Alzheimer’s disease (AD) highlights the importance of predicting lifetime risk and updating assessments as new data emerge. This study aimed to develop a dynamic model using longitudinal cognitive assessments for...
by Clinical Neuropsychologist Online | Wednesday, March 5, 2025 | Neuroscience
CNS 2025 Q&A with André Bastos In some moments in time, technology seems to catch up with theory in powerful ways to elucidate new truths about fundamental processes in the brain. Now is that moment for understanding how brain rhythms coordinate to make everyday...
