by Clinical Neuropsychologist Online | Saturday, March 29, 2025 | Dementia
Abstract INTRODUCTION Physical exercise is a primary defense against age-related cognitive decline and Alzheimer’s disease (AD). METHODS We conducted single-nucleus transcriptomic and chromatin accessibility analyses (snRNA-seq and snATAC-seq) on the hippocampus...
by Clinical Neuropsychologist Online | Saturday, March 29, 2025 | Dementia
Abstract INTRODUCTION Cerebral amyloid angiopathy (CAA) is characterized by the deposition of beta-amyloid (Aβ) in small vessels leading to hemorrhagic stroke and dementia. This study examined whether plasma Aβ42/40, phosphorylated-tau (p-tau), neurofilament light...
by Clinical Neuropsychologist Online | Saturday, March 29, 2025 | Dementia
Abstract INTRODUCTION Mixed evidence on how statin use affects risk of Alzheimer’s disease and related dementias (ADRD) may reflect heterogeneity across sociodemographic factors. Few studies have sufficient power to evaluate effect modifiers. METHODS Kaiser...
by Clinical Neuropsychologist Online | Saturday, March 29, 2025 | Neuropsychology (general)
Abstract This study used fMRI to examine the effect that the abstract-concrete dimension may have on the thematic-taxonomic distinction. The dual hub theory (DHT) posits that left angular gyrus supports thematic relationships and left temporal pole supports taxonomic...
by Clinical Neuropsychologist Online | Saturday, March 29, 2025 | Dementia
Abstract INTRODUCTION Comorbid conditions associated with Alzheimer’s disease (AD) are poorly understood regarding timing and potential impact on disease onset and progression. METHODS Medical Information Mart for Intensive Care-IV electronic health records from...
