by Clinical Neuropsychologist Online | Thursday, November 20, 2025 | Dementia
Dementia, Ahead of Print. Polypharmacy (taking five or more regular medications) is common in people with dementia or mild cognitive impairment (MCI) and is associated with poor outcomes such as decline in cognitive and physical functioning, falls and hospital...
by Clinical Neuropsychologist Online | Thursday, November 20, 2025 | Neuropsychology (general)
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by Clinical Neuropsychologist Online | Thursday, November 20, 2025 | Neuroscience
Nature Neuroscience, Published online: 20 November 2025; doi:10.1038/s41593-025-02138-3Early tactile deficits in patients with Alzheimer disease (AD) and AD mouse models map to tau pathology in spinal cholecystokinin (CCK) neurons. In AD mice, reducing tau or c-Maf...
by Clinical Neuropsychologist Online | Thursday, November 20, 2025 | Neuroscience
Nature Neuroscience, Published online: 20 November 2025; doi:10.1038/s41593-025-02079-xThe dopamine motivating animals to perform a current behavior also desensitizes local D2 dopamine receptors. Dopamine signaling is less effective in subsequent rounds, resulting in...
by Clinical Neuropsychologist Online | Wednesday, November 19, 2025 | Dementia
Dementia, Ahead of Print. The prevalence of dementia among Black families of African descent in Canada is projected to rise by 507%, according toThe Many Faces of Dementia in Canadareport. Despite this forecast, there remains a significant empirical gap regarding the...
