by Clinical Neuropsychologist Online | Monday, August 10, 2026 | Dementia
Abstract INTRODUCTION Alzheimer’s disease (AD) features amyloid beta (Aβ) plaques and tau tangles, yet how their coexistence reshapes brain transcriptomic programs remains unclear. METHODS We performed high-quality, sex-balanced single-nucleus RNA sequencing of...
by Clinical Neuropsychologist Online | Monday, August 10, 2026 | Dementia
Abstract INTRODUCTION Alzheimer’s disease neuropathologic change (ADNC) and limbic-predominant age-related transactive response DNA-binding protein 43 kDa (TDP-43) encephalopathy neuropathologic change (LATENC) are common in older adults, yet differences in...
by Clinical Neuropsychologist Online | Monday, August 10, 2026 | Dementia
Abstract INTRODUCTION Little research has assessed detailed occupational exposures in relation to the dementia exposome. We characterized patterns of multidimensional workplace stressors in relation to cognitive trajectories and racial disparities. METHODS We included...
by Clinical Neuropsychologist Online | Monday, August 10, 2026 | Dementia
Abstract INTRODUCTION Subjective cognitive concerns frequently diverge from objective cognitive performance in cognitively unimpaired (CU) older adults, yet the neurobiological basis of this mismatch remains unclear. METHODS In 648 participants from the Investigating...
by Clinical Neuropsychologist Online | Monday, August 10, 2026 | Neurorehabilitation
Neurorehabilitation and Neural Repair, Ahead of Print. Introduction:Accurate evaluation of upper limb recovery after stroke is essential for guiding rehabilitation targeting specific impairments and activity limitations. To achieve this, outcome measures must clearly...
