by Clinical Neuropsychologist Online | Thursday, August 27, 2026 | Neurorehabilitation
Neurorehabilitation and Neural Repair, Ahead of Print. Background:The TWIST algorithm was developed to predict the time to walk independently after stroke based on clinical assessments performed 1 week poststroke. The objective of this study was to externally validate...
by Clinical Neuropsychologist Online | Wednesday, August 26, 2026 | Dementia
Abstract INTRODUCTION Functional brain network alterations associated with Alzheimer’s disease (AD) pathology, including amyloid beta (Aβ) and phosphorylated tau (p-tau), are difficult to interpret due to overlapping aging-associated and non-amyloid biological...
by Clinical Neuropsychologist Online | Wednesday, August 26, 2026 | Dementia
Abstract In clinical studies, it is scientifically important, and a regulatory expectation, that objectives be translated into key clinical questions by specifically defining treatment effects to be estimated. Estimands are part of a structured framework, as presented...
by Clinical Neuropsychologist Online | Wednesday, August 26, 2026 | Dementia
Abstract INTRODUCTION Modifiers of the association between hormone replacement therapy (HRT) use and dementia risk and responsive subgroups, are unknown. METHODS In 183,450 postmenopausal women from the UK Biobank (mean 13.3 years follow-up), multivariable Cox...
by Clinical Neuropsychologist Online | Wednesday, August 26, 2026 | Dementia
Abstract INTRODUCTION We evaluated whether apolipoprotein E (APOE εε4) genotype-guided lecanemab escalation mitigates the APOE εε4–driven amyloid-related imaging abnormalities (ARIA) with edema (ARIA-E) gradient and whether ARIA-E and ARIA with hemosiderin deposition...
