by Clinical Neuropsychologist Online | Sunday, November 1, 2026 | Dementia
Abstract Mild cognitive impairment (MCI) is increasingly measured using routinely collected health-care data in embedded pragmatic clinical trials. However, accurate ascertainment remains challenging because key diagnostic elements, such as cognitive function and...
by Clinical Neuropsychologist Online | Sunday, November 1, 2026 | Dementia
Abstract INTRODUCTION We investigated associations of Area Deprivation Index (ADI) with Alzheimer’s disease (AD) -related outcomes by biological and social factors in at-risk older adults. METHODS A total of 1880 U.S. POINTER participants with ADI and cognition...
by Clinical Neuropsychologist Online | Sunday, November 1, 2026 | Dementia
Abstract BACKGROUND Reduced kidney function affects the levels of many Alzheimer’s disease and related dementias (ADRD) blood-based biomarkers (BBMs). The extent to which kidney function is associated with serum levels of brain-derived tau (BD-tau), a novel BBM...
by Clinical Neuropsychologist Online | Sunday, November 1, 2026 | Dementia
Abstract INTRODUCTION Sleep disturbances are common in older adults and linked to cognitive decline, but their association with functional abilities such as financial and health literacy is less understood. METHODS Participants without dementia from the Rush Memory...
by Clinical Neuropsychologist Online | Sunday, November 1, 2026 | Dementia
Abstract INTRODUCTION We evaluated a multimodal magnetic resonance imaging (MRI)-derived glymphatic-related composite and examined its associations with cardiovascular risk, brain structural integrity, and cognition in older adults. METHODS Ninety-two participants...
