Nature Neuroscience, Published online: 24 November 2025; doi:10.1038/s41593-025-02117-8Engineering human microglia with a Down-syndrome-linked myeloid gene variant resists tau-induced dysfunction and protects neurons in chimeric brains, offering proof of concept for transformative microglial replacement therapies in Alzheimer’s disease.
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This post is Copyright: | November 24, 2025
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