Nature Neuroscience, Published online: 20 October 2026; doi:10.1038/s41593-026-02487-7This study identifies ABCA1 as a driver of dysregulated cholesterol trafficking in Parkinson’s disease, showing that reducing ABCA1 in astrocytes and neurons decreases cholesterol accumulation, α-synuclein pathology and neurodegeneration in mice.


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This post is Copyright: | October 20, 2026
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