Nature Neuroscience, Published online: 02 July 2024; doi:10.1038/s41593-024-01677-5The molecular mechanisms underlying direct neuronal reprogramming are unclear. Here the authors show Ngn2-mediated chromatin remodeling and its binding sites underlying mouse astrocyte-to-neuron reprogramming and identify Yy1, a transcription co-factor, as an important regulator.
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This post is Copyright: Allwyn Pereira | July 2, 2024
Nature Neuroscience