Nature Neuroscience, Published online: 24 December 2024; doi:10.1038/s41593-024-01829-7Mice expressing humanized mutant tau exhibit synaptic loss and behavioral abnormalities in the absence of abnormal tau conformers, suggesting that hyperphosphorylated tau can be pathological, at least in tauopathies caused by tau isoform imbalance.
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This post is Copyright: Naoto Watamura | December 24, 2024
Nature Neuroscience