by Clinical Neuropsychologist | Friday, October 25, 2024 | Dementia
Abstract BACKGROUND Synaptic and extrasynaptic distribution of N-methyl-D-aspartate receptors (NMDARs) has not been addressed in the brain from Alzheimer´s disease (AD) subjects, despite their contribution to neurodegeneration. METHODS We have developed a protocol to...
by Clinical Neuropsychologist | Friday, October 25, 2024 | Neuropsychology (general)
Abstract Biological, clinicobiological and clinical conceptions of Alzheimer’s disease and related dementias are being promoted simultaneously to different practical ends. The co-existence of contemporary conceptions and the ‘scary label’ associated with older...
by Clinical Neuropsychologist | Friday, October 25, 2024 | Neuroscience
Nature Neuroscience, Published online: 25 October 2024; doi:10.1038/s41593-024-01790-5Undergraduate research programs improve career outcomes for historically marginalized students in the US, but low retention rates in postgraduate research persist. As graduate...
by Clinical Neuropsychologist | Thursday, October 24, 2024 | Dementia
Abstract INTRODUCTION Emerging preclinical evidence suggests that semaglutide, a glucagon-like peptide receptor agonist (GLP-1RA) for type 2 diabetes mellitus (T2DM) and obesity, protects against neurodegeneration and neuroinflammation. However, real-world evidence...
by Clinical Neuropsychologist | Thursday, October 24, 2024 | Dementia
Abstract INTRODUCTION This study evaluated the associations between Life’s Essential 8 (LE8) and cognitive performance, and compared the strength of the relationships of Life’s Simple 7 (LS7) and LE8 to cognition in midlife and older adults. METHODS...