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The Importance of Synapses in Alzheimer’s Disease

by Clinical Neuropsychologist | Tuesday, December 23, 2025 | Neuroscience

Alzheimer’s disease is one of the most pressing medical issues of our time. In this lecture, Spires-Jones discusses advances in understanding the role of synapses in disease pathogenesis, including the accumulation of pathological proteins within synapses, the...

Cognition Emerges From Neural Dynamics

by Clinical Neuropsychologist | Tuesday, December 23, 2025 | Neuroscience

Classic models likened brain function to neuron networks, like telegraph systems. Emerging evidence, however, suggests higher cognition relies on rhythmic oscillations or “brain waves” at the electric field level. If you do not see content above, kindly GO...

Dialogues Between Neuroscience and Society: Transforming Wine Appreciation from Sensory Experience to Mastery with Nicolas Quillé

by Clinical Neuropsychologist | Monday, December 22, 2025 | Neuroscience

This Dialogues Between Neuroscience and Society lecture was recorded ;Nov. ;15, 2025, at Neuroscience 2025 ;in ;San Diego.   Nicolas ;Quillé, MW, highly credentialed wine professional, presents ;his framework for understanding wine tasting in the style of Robert...

Genetic mapping identifies Homer1 as a developmental modifier of attention

by Clinical Neuropsychologist | Monday, December 22, 2025 | Neuroscience

Nature Neuroscience, Published online: 22 December 2025; doi:10.1038/s41593-025-02155-2Genetic mapping in mice identified Homer1a as a key modifier of attention. Developmental downregulation in the prefrontal cortex enhances inhibitory tone, neural signal to noise and...

Extracellular matrix proteolysis maintains synapse plasticity during brain development

by Clinical Neuropsychologist | Monday, December 22, 2025 | Neuroscience

Nature Neuroscience, Published online: 22 December 2025; doi:10.1038/s41593-025-02153-4This study demonstrates that the extracellular matrix (ECM) of the developing brain stabilizes recently born synapses. The authors identify a microglial metalloprotease that digests...
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