by Clinical Neuropsychologist Online | Thursday, August 6, 2026 | Neuroscience
Nature Neuroscience, Published online: 06 August 2026; doi:10.1038/s41593-026-02375-0Chiu et al. have developed engineered HTR2A mouse lines enabling in vivo mapping, targeting and modulation of receptor-expressing neurons and validated their utility across...
by Clinical Neuropsychologist Online | Thursday, August 6, 2026 | Neuroscience
Nature Neuroscience, Published online: 06 August 2026; doi:10.1038/s41593-026-02397-8This study finds that shed NLGN3 interacts with the glycosylated surface protein CSPG4 on both normal and malignant glial cells, activating mechanotransduction pathways that drive...
by Clinical Neuropsychologist Online | Thursday, August 6, 2026 | Neuroscience
Nature Neuroscience, Published online: 06 August 2026; doi:10.1038/s41593-026-02380-3Charbonneau et al. compare how the insula is structured and functions in humans, monkeys and rodents, revealing similarities and differences across species that are likely to impact...
by Clinical Neuropsychologist Online | Wednesday, August 5, 2026 | Dementia
Abstract INTRODUCTION Animal models demonstrated that pharmacologically-induced lesioning of the locus coeruleus (LC), the brain’s primary source of norepinephrine, triggered astrocyte reactivity, exacerbating Alzheimer’s disease (AD) pathology and...
by Clinical Neuropsychologist Online | Wednesday, August 5, 2026 | Dementia
Abstract INTRODUCTION Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) is a prodromal phase of Lewy body diseases and linked to a high risk for cognitive decline. Therefore, iRBD provides a suitable window for early intervention. METHODS In the...
