by Clinical Neuropsychologist Online | Friday, November 21, 2025 | Neuroscience
Nature Neuroscience, Published online: 21 November 2025; doi:10.1038/s41593-025-02115-wAstrocytes are associated with Alzheimer’s disease pathogenesis. We found that the transcription factor Sox9 functions to enhance astrocytic phagocytosis of Aβ plaques via MEGF10,...
by Clinical Neuropsychologist Online | Thursday, November 20, 2025 | Dementia
Dementia, Ahead of Print. Background:People with dementia experience discrimination and treatment that contravenes their human rights in health and social care settings. Human Rights law is complex, and real-world application can be confusing. Researchers used the...
by Clinical Neuropsychologist Online | Thursday, November 20, 2025 | Dementia
Dementia, Ahead of Print. Polypharmacy (taking five or more regular medications) is common in people with dementia or mild cognitive impairment (MCI) and is associated with poor outcomes such as decline in cognitive and physical functioning, falls and hospital...
by Clinical Neuropsychologist Online | Thursday, November 20, 2025 | Neuropsychology (general)
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by Clinical Neuropsychologist Online | Thursday, November 20, 2025 | Neuroscience
Nature Neuroscience, Published online: 20 November 2025; doi:10.1038/s41593-025-02079-xThe dopamine motivating animals to perform a current behavior also desensitizes local D2 dopamine receptors. Dopamine signaling is less effective in subsequent rounds, resulting in...