by Clinical Neuropsychologist | Monday, January 6, 2025 | Neuroscience
Nature Neuroscience, Published online: 06 January 2025; doi:10.1038/s41593-024-01833-xMicroglia are proposed to have a role in brain development through synaptic engulfment and paracrine signaling. O’Keeffe et al. show that certain neurodevelopmental processes...
by Clinical Neuropsychologist | Monday, January 6, 2025 | Neuroscience
Nature Neuroscience, Published online: 06 January 2025; doi:10.1038/s41593-024-01847-5This article discusses a puzzling issue in brain pathology: why brain-resident microglia are insufficient for protection, and why myeloid cells are needed from the periphery. Several...
by Clinical Neuropsychologist | Friday, January 3, 2025 | Dementia
Abstract Background Alzheimer’s disease (AD) is a complex neurodegenerative disorder characterized by hallmark pathologies that affect many brain regions, including the cellular microenvironment with the hippocampus, ultimately leading to profound deficits in...
by Clinical Neuropsychologist | Friday, January 3, 2025 | Dementia
Abstract Background MicroRNAs have been linked to dementia. However, understanding their relation to cognition in the general population is required to determine their potential use for the detection and prevention of age-associated cognitive decline and preclinical...
by Clinical Neuropsychologist | Friday, January 3, 2025 | Dementia
Abstract Understanding the physiological connection between platelets and brain function reveals new paradigms in neurodegenerative disease treatment. Platelets, traditionally associated with hemostasis, but also sometimes regarded as a mirror of neurons in the blood...