by Clinical Neuropsychologist | Friday, January 3, 2025 | Dementia
Abstract Background Despite significant advancements in the development of blood biomarkers for AD, challenges persist due to the complex interplay of genetic and environmental risk factors in AD pathogenesis. Epigenetic processes, including non-coding RNAs and...
by Clinical Neuropsychologist | Friday, January 3, 2025 | Dementia
Abstract Background MicroRNAs have been linked to dementia. However, understanding their relation to cognition in the general population is required to determine their potential use for the detection and prevention of age-associated cognitive decline and preclinical...
by Clinical Neuropsychologist | Thursday, January 2, 2025 | Dementia
Abstract INTRODUCTION Whole genome methylation sequencing (WGMS) in blood identifies differential DNA methylation in persons with late-onset dementia due to Alzheimer’s disease (AD) but has not been tested in persons with mild cognitive impairment (MCI). METHODS...
by Clinical Neuropsychologist | Thursday, January 2, 2025 | Neuroscience
Nature Neuroscience, Published online: 02 January 2025; doi:10.1038/s41593-024-01817-xMice react differently to others’ stress depending on their own past experience of the same (but not different) stress. Corticotropin-releasing factor (CRF) neuron activity in the...
by Clinical Neuropsychologist | Thursday, January 2, 2025 | Neuroscience
Nature Neuroscience, Published online: 02 January 2025; doi:10.1038/s41593-024-01807-zThis study shows that cerebellar Bergmann glia process noxious stimuli by integrating signals from the locus coeruleus. This mechanism modulates pain-related behaviors. These...
