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Rethinking tau‐targeted therapy in Alzheimer’s disease: Toward a dual biomarker strategy

by Clinical Neuropsychologist Online | Thursday, September 17, 2026 | Dementia

Abstract Tau pathology is more closely associated with cognitive deterioration than amyloid burden in symptomatic Alzheimer’s disease (AD), yet tau-targeted trials have often interpreted decreases in soluble phosphorylated tau (p-tau) as evidence of therapeutic...

Operationalizing Alzheimer’s disease trials in the era of targeted therapies

by Clinical Neuropsychologist Online | Thursday, September 17, 2026 | Dementia

Abstract The therapeutic landscape of Alzheimer’s disease (AD) is rapidly evolving with the clinical adoption of anti-amyloid monoclonal antibodies (mAbs) despite an incomplete understanding of disease mechanisms, progression, and heterogeneity. Designing both...

Hippocampal snRNA‐seq in Collaborative Cross reveals molecular signatures of cognitive resilience independent of chronological aging

by Clinical Neuropsychologist Online | Thursday, September 17, 2026 | Dementia

Abstract INTRODUCTION Genetic factors contribute to variability in age-related cognitive decline, yet the molecular mechanisms underlying cognitive resilience remain poorly understood. METHODS We performed single-nucleus RNA sequencing on hippocampal tissue from 107...

Mechanism of change in functional neurological (motor) disorder: a pilot study using a single-case experimental design

by Clinical Neuropsychologist Online | Wednesday, September 16, 2026 | Neurorehabilitation

. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: | September 16, 2026 Neuro-Rehab Previous Page

Longitudinal changes in social cognition in early relapsing-remitting multiple sclerosis over two years

by Clinical Neuropsychologist Online | Wednesday, September 16, 2026 | Neuropsychology (general)

. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: | September 16, 2026 Neuro-General Previous Page
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