by Clinical Neuropsychologist | Monday, August 11, 2025 | Neuroscience
Nature Neuroscience, Published online: 11 August 2025; doi:10.1038/s41593-025-02032-yActivation of Gs signaling at mitochondria by mitoDREADD-Gs increases mitochondrial metabolism, leading to better memory in mouse models of dementia, directly linking brain...
by Clinical Neuropsychologist | Monday, August 11, 2025 | Neuroscience
Nature Neuroscience, Published online: 11 August 2025; doi:10.1038/s41593-025-02027-9Machine-learning-augmented single-nucleus transcriptomic analysis compared molecular landscapes of immature neurons in the mammalian hippocampus across species, highlighting...
by Clinical Neuropsychologist | Monday, August 11, 2025 | Neuroscience
Nature Neuroscience, Published online: 11 August 2025; doi:10.1038/s41593-025-02013-1The principal layer architecture of the sensory cortex is altered with aging. The authors show that overall thinning of the primary somatosensory cortex is driven by deep layer...
by Clinical Neuropsychologist | Monday, August 11, 2025 | Neuroscience
Nature Neuroscience, Published online: 11 August 2025; doi:10.1038/s41593-025-02039-5By selectively isolating and sequencing the rare RNA transcripts containing C9orf72 repeat expansion from ALS–FTD neurons, the authors uncover an alternative splicing mechanism that...
by Clinical Neuropsychologist | Monday, August 11, 2025 | Neuroscience
Nature Neuroscience, Published online: 11 August 2025; doi:10.1038/s41593-025-02040-yThe mechanisms linking neuropsychiatric and metabolic disorders remain unclear. The authors show a pancreas–hippocampus feedback loop whereby metabolic and circadian factors drive...
