by Clinical Neuropsychologist Online | Monday, February 24, 2025 | Dementia
Abstract INTRODUCTION We investigated the moderating effects of midlife and late-life cognitive activity (CA) on the relationship between tau pathology and both cognition and cognitive decline. METHODS Eighty-nine non-demented older adults from a Korean cohort...
by Clinical Neuropsychologist Online | Monday, February 24, 2025 | Neuroscience
Nature Neuroscience, Published online: 24 February 2025; doi:10.1038/s41593-025-01878-6White matter (WM) astrocytes differ significantly from gray matter astrocytes, with WM astrocytes in the forebrain exhibiting unique proliferation capacity, which is absent in...
by Clinical Neuropsychologist Online | Monday, February 24, 2025 | Neuroscience
Nature Neuroscience, Published online: 24 February 2025; doi:10.1038/s41593-025-01882-wSocioeconomic status is multidimensional and can change over time. Xu, Lui, Ji et al. found dimension-specific, late-stage-specific and change-specific socioeconomic effects on...
by Clinical Neuropsychologist Online | Monday, February 24, 2025 | Neuroscience
Nature Neuroscience, Published online: 24 February 2025; doi:10.1038/s41593-024-01865-3The authors show PTEN mutations, which can cause both congenital hydrocephalus and autism spectrum disorder, disrupt CSF homeostasis and brain connectivity in mice. Reducing mTORC1...
by Clinical Neuropsychologist Online | Saturday, February 22, 2025 | Dementia
Abstract INTRODUCTION Isolated REM sleep behavior disorder (iRBD) is a strong prodromal marker of Lewy body diseases (LBDs) – Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). Cholinergic loss is linked to cognitive decline in these conditions, but...
