by Clinical Neuropsychologist Online | Thursday, February 6, 2025 | Neuroscience
Nature Neuroscience, Published online: 06 February 2025; doi:10.1038/s41593-025-01886-6Non-REM sleep substates separate old and new memories If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at...
by Clinical Neuropsychologist Online | Wednesday, February 5, 2025 | Dementia
Abstract INTRODUCTION The Alzheimer’s Association Global Biomarker Standardization Consortium conducted a blinded case–control study to learn which phosphorylated tau (p-tau) assays provide the largest fold-changes in Alzheimer’s disease (AD) versus non-AD...
by Clinical Neuropsychologist Online | Wednesday, February 5, 2025 | Dementia
Abstract INTRODUCTION Research on somatic and germline mutations in Chinese individuals with early-onset Alzheimer’s disease (EOAD) has been limited. METHODS We conducted whole-genome sequencing of blood DNA from 108 patients with EOAD and 116 controls. The...
by Clinical Neuropsychologist Online | Wednesday, February 5, 2025 | Dementia
Abstract INTRODUCTION This study aimed to investigate the differential roles of various plasma biomarkers in a stepwise diagnostic strategy for Alzheimer’s disease (AD). METHODS A total of 2984 participants, including 666 cognitively unimpaired (CU), 2032 with...
by Clinical Neuropsychologist Online | Tuesday, February 4, 2025 | Neuroimaging
ABSTRACT Background and Purpose This study investigated the neural mechanisms underlying Parkinson’s disease (PD) subtypes—tremor dominant (TD) and postural instability gait difficulty (PIGD)—by analyzing regional homogeneity (ReHo) values from resting-state...
