by Clinical Neuropsychologist Online | Tuesday, January 14, 2025 | Dementia
Abstract INTRODUCTION Using an Asian cohort with high prevalence of concomitant cerebrovascular disease (CeVD), we evaluated the performance of a plasma immunoassay for tau phosphorylated at threonine 217 (p-tau217) in detecting amyloid beta positivity (Aβ+) on...
by Clinical Neuropsychologist Online | Tuesday, January 14, 2025 | Dementia
Abstract Observational studies on the cancer–dementia relationship have yielded controversial results. This study systematically reviews the evidence to clarify this association. We searched Embase, Global Health, Ovid Medline, and APA PsycInfo. Colorectal and lung...
by Clinical Neuropsychologist Online | Tuesday, January 14, 2025 | Dementia
Abstract INTRODUCTION Successful cognitive aging is related to both maintaining brain structure and avoiding Alzheimer’s disease (AD) pathology, but how these factors interplay is unclear. METHODS A total of 109 cognitively normal older adults (70+ years old)...
by Clinical Neuropsychologist Online | Tuesday, January 14, 2025 | Dementia
Abstract INTRODUCTION Interferon-induced transmembrane protein 3 (IFITM3) modulates γ-secretase in Alzheimer’s Disease (AD). Although IFITM3 knockout reduces amyloid β protein (Aβ) production, its cell-specific effect on AD remains unclear. METHODS Single...
by Clinical Neuropsychologist Online | Monday, January 13, 2025 | Neuroimaging
ABSTRACT Background and Purpose While the pulsatility index (PI) measured by transcranial Doppler (TCD) has broader associations with outcomes in neurocritical care, its use in monitoring delayed cerebral infarction (DCI) in patients with aneurysmal subarachnoid...
