by Clinical Neuropsychologist Online | Thursday, January 9, 2025 | Neuroimaging
ABSTRACT Background and Purpose Peak width of skeletonized mean diffusivity (PSMD) is a novel marker of white matter damage, which may be related to small vessel disease. This study aimed to investigate the presence of white matter damage in patients with isolated...
by Clinical Neuropsychologist Online | Thursday, January 9, 2025 | Neuroimaging
ABSTRACT Introduction The venous outflow profile (VOP) is a crucial yet often overlooked aspect affecting stroke outcomes. It plays a major role in the physiopathology of acute cerebral ischemia, as it accounts for both the upstream arterial collaterals and cerebral...
by Clinical Neuropsychologist Online | Thursday, January 9, 2025 | Dementia
Abstract INTRODUCTION Menopausal hormone therapy (MHT), along with the apolipoprotein E (APOE) ε4 allele, has been suggested as a possible risk factor for Alzheimer’s disease (AD). However, the relationship between MHT and cerebrospinal fluid (CSF) biomarkers is...
by Clinical Neuropsychologist Online | Thursday, January 9, 2025 | Dementia
Abstract Background We analyzed the clinical care pathway of patients from symptom development to diagnosis at varying stages of Alzheimer’s disease (AD) to understand the path and barriers to diagnosis. Methods Data were from the US Adelphi Real World Dementia...
by Clinical Neuropsychologist Online | Thursday, January 9, 2025 | Dementia
Abstract Background Insulin Resistance (IR) is implicated in brain aging and Alzheimer’s disease (AD) pathogenesis. Dietary changes may promote brain health in older adults with metabolic abnormalities. An extensive animal literature suggests pro-cognitive and...