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A multi‐view learning approach with diffusion model to synthesize FDG PET from MRI T1WI for diagnosis of Alzheimer’s disease

by Clinical Neuropsychologist Online | Friday, December 6, 2024 | Dementia

Abstract INTRODUCTION This study presents a novel multi-view learning approach for machine learning (ML)–based Alzheimer’s disease (AD) diagnosis. METHODS A diffusion model is proposed to synthesize the fluorodeoxyglucose positron emission tomography (FDG PET)...

The POINTER Imaging baseline cohort: Associations between multimodal neuroimaging biomarkers, cardiovascular health, and cognition

by Clinical Neuropsychologist Online | Friday, December 6, 2024 | Dementia

Abstract INTRODUCTION The U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk (U.S. POINTER) is evaluating lifestyle interventions in older adults at risk for cognitive decline and dementia. Here we characterize the baseline data set of...

Association of ten VEGF family genes with Alzheimer’s disease endophenotypes at single cell resolution

by Clinical Neuropsychologist Online | Friday, December 6, 2024 | Dementia

Abstract INTRODUCTION Using a single-nucleus transcriptome derived from the dorsolateral prefrontal cortex of 424 Religious Orders Study and the Rush Memory and Aging Project (ROS/MAP) participants, we investigated the cell type–specific effect of ten vascular...

Author Correction: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

by Clinical Neuropsychologist Online | Friday, December 6, 2024 | Neuroscience

Nature Neuroscience, Published online: 06 December 2024; doi:10.1038/s41593-024-01853-7Author Correction: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction If you do not see content above,...

Evaluating performance and quality of a fast multi‐contrast scan in routine brain MRI

by Clinical Neuropsychologist Online | Thursday, December 5, 2024 | Neuroimaging

Abstract Background and Purpose Neuromix is a fast, motion robust multi-contrast sequence capable of providing all diagnostic contrasts in ∼3.5 minutes. However, more evaluation is needed across the various contrasts compared to gold standard, optimized sequences...
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