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Tibial bone compression promotes recovery after brain injury through osteocyte PIEZO1

by Clinical Neuropsychologist Online | Monday, September 21, 2026 | Neuroscience

Nature Neuroscience, Published online: 21 September 2026; doi:10.1038/s41593-026-02422-wMechanical loading of the tibia improves survival and recovery after brain surgery in mice and pigs. This bone–brain axis is mediated by osteocyte PIEZO1, which triggers the...

Aβ1‐40 induces venular endothelial cell ferroptosis in cerebral amyloid angiopathy via the ATF3/xCT axis: Insights from single‐cell RNA sequencing

by Clinical Neuropsychologist Online | Monday, September 21, 2026 | Dementia

Abstract INTRODUCTION Amyloid-beta (Aβ)-induced microvascular injury is a key pathological feature of cerebral amyloid angiopathy (CAA). Recent evidence suggests that ferroptosis is implicated in Aβ pathology; however, its cell-type specificity and regulatory...

Genetic evidence suggests a protective role of immunoglobulin M in Alzheimer’s disease

by Clinical Neuropsychologist Online | Monday, September 21, 2026 | Dementia

Abstract INTRODUCTION Immune dysfunction has been implicated in Alzheimer’s disease (AD), but the roles of specific immunoglobulin classes remain unclear. METHODS We integrated human genetics and plasma biomarker analyses to evaluate immunoglobulin G (IgG), IgA,...

Clinical modifiers of the association between type 1 diabetes and dementia incidence

by Clinical Neuropsychologist Online | Monday, September 21, 2026 | Dementia

Abstract INTRODUCTION Type 1 diabetes mellitus (T1DM) increases dementia risk. Understanding clinical modifiers of that effect could inform prevention. METHODS We analyzed data from All of Us. Participants were aged ≥50 years with T1DM (n = 5,442) or no diabetes...

Correction to “Human iPSC‐derived GABAergic interneuron transplantation restores circuit balance and cognitive function in an Alzheimer’s disease model”

by Clinical Neuropsychologist Online | Monday, September 21, 2026 | Dementia

Alzheimer’s &Dementia, Volume 22, Issue 9, September 2026. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: | September 21, 2026 Neuro-Dementia...
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