by Clinical Neuropsychologist Online | Tuesday, August 11, 2026 | Neuroscience
Nature Neuroscience, Published online: 11 August 2026; doi:10.1038/s41593-026-02416-8On 11 July 2026, neuroscience lost one of its most visionary scientists with the passing of Susumu Tonegawa at the age of 86. Across an extraordinary career spanning more than five...
by Clinical Neuropsychologist Online | Monday, August 10, 2026 | Dementia
Abstract INTRODUCTION Alzheimer’s disease (AD) features amyloid beta (Aβ) plaques and tau tangles, yet how their coexistence reshapes brain transcriptomic programs remains unclear. METHODS We performed high-quality, sex-balanced single-nucleus RNA sequencing of...
by Clinical Neuropsychologist Online | Monday, August 10, 2026 | Dementia
Abstract INTRODUCTION Alzheimer’s disease neuropathologic change (ADNC) and limbic-predominant age-related transactive response DNA-binding protein 43 kDa (TDP-43) encephalopathy neuropathologic change (LATENC) are common in older adults, yet differences in...
by Clinical Neuropsychologist Online | Monday, August 10, 2026 | Dementia
Abstract INTRODUCTION Little research has assessed detailed occupational exposures in relation to the dementia exposome. We characterized patterns of multidimensional workplace stressors in relation to cognitive trajectories and racial disparities. METHODS We included...
by Clinical Neuropsychologist Online | Monday, August 10, 2026 | Dementia
Abstract INTRODUCTION Subjective cognitive concerns frequently diverge from objective cognitive performance in cognitively unimpaired (CU) older adults, yet the neurobiological basis of this mismatch remains unclear. METHODS In 648 participants from the Investigating...
