by Clinical Neuropsychologist Online | Wednesday, November 13, 2024 | Dementia
Abstract White matter hyperintensities (WMH) and infarcts found on magnetic resonance imaging (MR infarcts) are common biomarkers of cerebrovascular disease. In this review, we summarize the methods, publications, and conclusions stemming from the Alzheimer’s...
by Clinical Neuropsychologist Online | Tuesday, November 12, 2024 | Dementia
Abstract INTRODUCTION We investigate sex-specific topological structures associated with typical Alzheimer’s disease (AD) dementia using a novel state-of-the-art latent space estimation technique. METHODS This study applies a probabilistic approach for latent...
by Clinical Neuropsychologist Online | Monday, November 11, 2024 | Neuro Podcasts
In this episode of Naked Neuroscience, James Tytko is investigating what harms smartphones might be inflicting on adolescents. He hears from a collective action group seeking to delay giving phones to their children, neuropsychologist Richard Cytowic describes the...
by Clinical Neuropsychologist Online | Monday, November 11, 2024 | Neuroscience
Nature Neuroscience, Published online: 11 November 2024; doi:10.1038/s41593-024-01777-2Tyrosine kinase 2 (TYK2) critically regulates tau levels and aggregation by phosphorylating tau’s tyrosine 29. Partial inhibition of TYK2 mitigates tau pathologies in cells and...
by Clinical Neuropsychologist Online | Monday, November 11, 2024 | Neuroscience
Nature Neuroscience, Published online: 11 November 2024; doi:10.1038/s41593-024-01791-4Using single-nucleus RNA sequencing from 32 donors, researchers identified distinct astrocytic gene expression programs activated across brain regions and Alzheimer’s disease...
