by Clinical Neuropsychologist | Monday, March 31, 2025 | Neuroscience
Nature Neuroscience, Published online: 31 March 2025; doi:10.1038/s41593-025-01922-5Kim and coworkers describe a technique, EPSILON, to map AMPA receptor exocytosis, a proxy for synaptic plasticity, in mice. The authors demonstrated a correlation between AMPA receptor...
by Clinical Neuropsychologist | Monday, March 31, 2025 | Neuroscience
Nature Neuroscience, Published online: 31 March 2025; doi:10.1038/s41593-025-01923-4Researchers developed DELTA, a method for brain-wide measurement of synaptic protein turnover with single-synapse resolution, providing a powerful tool to localize and study mechanisms...
by Clinical Neuropsychologist | Saturday, March 29, 2025 | Dementia
Abstract INTRODUCTION This study was undertaken to evaluate the diagnostic performance of a novel plasma phosphorylated tau (p-tau) 217/amyloid beta (Aβ) 42 ratio test for Alzheimer’s disease (AD). METHODS The diagnostic performance of the Lumipulse G plasma...
by Clinical Neuropsychologist | Saturday, March 29, 2025 | Dementia
Abstract INTRODUCTION It is unclear whether aggregated plasma protein risk scores (PPRSs) could be useful in predicting the risks of mild cognitive impairment (MCI) and Alzheimer’s disease (AD). METHODS The Cox proportional hazard model with the Least Absolute...
by Clinical Neuropsychologist | Saturday, March 29, 2025 | Dementia
Abstract INTRODUCTION Accountable care organizations (ACOs) are well positioned to promote care coordination. However, robust evidence of ACOs’ impact on Medicare payments for residents with Alzheimer’s disease and related dementias (ADRD) in disadvantaged...