by Clinical Neuropsychologist Online | Wednesday, September 25, 2024 | Dementia
Abstract INTRODUCTION The Alzheimer’s Prevention Initiative (API) Generation Studies evaluated the BACE inhibitor umibecestat for Alzheimer’s disease (AD) prevention. The studies were terminated early, and the reversibility of umibecestat’s side...
by Clinical Neuropsychologist Online | Tuesday, September 24, 2024 | Dementia
Abstract The tauopathies are defined by pathological tau protein aggregates within a spectrum of clinically heterogeneous neurodegenerative diseases. The primary tauopathies meet the definition of rare diseases in the United States. There is no approved treatment for...
by Clinical Neuropsychologist Online | Tuesday, September 24, 2024 | Dementia
Abstract INTRODUCTION We investigated the prevalence of amyloid beta (Aβ) positivity (+) and cognitive trajectories in Koreans and non-Hispanic Whites (NHWs). METHODS We included 5121 Koreans from multiple centers across South Korea and 929 NHWs from the...
by Clinical Neuropsychologist Online | Tuesday, September 24, 2024 | Neurorehabilitation
Volume 27, Issue 7, October 2024, Page 217-227. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: Hiba Al-Hakeem Andrea Hickling Kylie D. Mallory Andrew...
by Clinical Neuropsychologist Online | Tuesday, September 24, 2024 | Neuroscience
Nature Neuroscience, Published online: 24 September 2024; doi:10.1038/s41593-024-01768-3The authors perform the first single-cell profiling of m6A in the mouse brain. They uncover relative hypomethylation of microglial mRNA compared to other cell types, and they...
