by Clinical Neuropsychologist | Thursday, March 27, 2025 | Neuro Podcasts
Would you rather read the transcript? Click here. Making it to 500 episodes is no joke, and I couldn’t have done it without the support of my amazing partner, Carrie. A therapist and podcaster herself, she has encouraged and challenged me countless times along the...
by Clinical Neuropsychologist | Wednesday, March 26, 2025 | Dementia
Abstract INTRODUCTION Alzheimer’s disease (AD) selectively affects certain brain regions, yet the mechanisms of selective vulnerability remain poorly understood. The neuromodulatory subcortical system, which includes nuclei exhibiting a range of vulnerability...
by Clinical Neuropsychologist | Wednesday, March 26, 2025 | Neuroimaging
ABSTRACT Background and Purpose 99mTc-TRODAT-1 SPECT imaging is an imaging technique, more commonly used in Asia, to diagnose Parkinson’s disease (PD). This study evaluates the use of automated three-dimensional volume-of-interest (VOI) analysis in diagnosing...
by Clinical Neuropsychologist | Wednesday, March 26, 2025 | Dementia
Abstract INTRODUCTION Plasma phosphorylated threonine 181 of tau (pTau181) and amyloid beta (Aβ) are biomarkers for differential diagnosis and preclinical detection of Alzheimer disease (AD). Given differences in AD risk across diverse populations,...
by Clinical Neuropsychologist | Wednesday, March 26, 2025 | Dementia
Abstract INTRODUCTION Distinguishing between molecular changes that precede dementia onset and those resulting from the disease is challenging with cross-sectional studies. METHODS We studied blood DNA methylation (DNAm) differences and incident dementia in two large...
