by Clinical Neuropsychologist Online | Monday, August 26, 2024 | Neuroscience
Nature Neuroscience, Published online: 26 August 2024; doi:10.1038/s41593-024-01737-wUsing human cerebrospinal fluid proteomics, the authors found that proteins associated with Aβ pathology in Alzheimer disease were mainly expressed in glial cells, whereas those...
by Clinical Neuropsychologist Online | Friday, August 23, 2024 | Neurorehabilitation
Neurorehabilitation and Neural Repair, Volume 38, Issue 11-12, Page 795-807, December 2024. BackgroundMobility and cognitive impairment are prevalent and co-occurring in older adults with multiple sclerosis (OAMS), yet there is limited research concerning the role of...
by Clinical Neuropsychologist Online | Friday, August 23, 2024 | Dementia
Abstract INTRODUCTION The in vivo detection of mixed Alzheimer’s disease (AD) and α-synuclein (αSyn) pathology is important for clinical management and prognostic stratification. We investigated the contribution of αSyn pathology, detected by cerebrospinal fluid...
by Clinical Neuropsychologist Online | Friday, August 23, 2024 | Dementia
Abstract INTRODUCTION We aimed to assess the impact of cholinesterase inhibitors (ChEIs) and memantine on cognition, major adverse cardiovascular events (MACE) and mortality in dementia with Lewy bodies (DLB). METHODS A total of 1,095 incident DLB patients from the...
by Clinical Neuropsychologist Online | Friday, August 23, 2024 | Dementia
Abstract INTRODUCTION The paramagnetic iron, diamagnetic amyloid beta (Aβ) plaques and their interaction are crucial in Alzheimer’s disease (AD) pathogenesis, complicating non-invasive magnetic resonance imaging for prodromal AD detection. METHODS We used a...
