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Reward prediction error neurons implement an efficient code for reward

by Clinical Neuropsychologist Online | Wednesday, June 19, 2024 | Neuroscience

Nature Neuroscience, Published online: 19 June 2024; doi:10.1038/s41593-024-01671-xThis theoretical study shows that dopaminergic reward prediction error neurons encode experienced rewards efficiently, which explains four major aspects of the neural population. This...

Apolipoprotein E in Alzheimer’s disease trajectories and the next-generation clinical care pathway

by Clinical Neuropsychologist Online | Wednesday, June 19, 2024 | Neuroscience

Nature Neuroscience, Published online: 19 June 2024; doi:10.1038/s41593-024-01669-5This Review provides a framework for incorporating APOE into Alzheimer’s disease (AD) clinical care by bridging recent advances in APOE and AD research with emerging clinical...

Effect of apolipoprotein E ε4 and its modification by sociodemographic characteristics on cognitive measures in South Asians from LASI‐DAD

by Clinical Neuropsychologist Online | Wednesday, June 19, 2024 | Dementia

Abstract BACKGROUND We investigated the effects of apolipoprotein E (APOE) ε4 and its interactions with sociodemographic characteristics on cognitive measures in South Asians from the Diagnostic Assessment of Dementia for the Longitudinal Aging Study of India...

Development of a prediction model for cognitive impairment of sarcopenia using multimodal neuroimaging in non‐demented older adults

by Clinical Neuropsychologist Online | Wednesday, June 19, 2024 | Dementia

Abstract INTRODUCTION Despite prior research on the association between sarcopenia and cognitive impairment in the elderly, a comprehensive model that integrates various brain pathologies is still lacking. METHODS We used data from 528 non-demented older adults with...

Care needs of people with dementia in Tanzania and associated impact on carers: A cross-sectional, observational study

by Clinical Neuropsychologist Online | Tuesday, June 18, 2024 | Dementia

Dementia, Volume 23, Issue 6, Page 1021-1035, August 2024. Objectives: This study aimed to understand the care needs, care arrangements and burden of care for people with dementia in Northern Tanzania. Methods: This was a cross-sectional, observational study. People...
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