by Clinical Neuropsychologist Online | Wednesday, May 22, 2024 | Neuroscience
Nature Neuroscience, Published online: 22 May 2024; doi:10.1038/s41593-024-01649-9This paper presents Simple Behavioral Analysis (SimBA), an open-source platform for automated, explainable machine learning analysis of behavior. SimBA comes with extensive...
by Clinical Neuropsychologist Online | Tuesday, May 21, 2024 | Dementia
Abstract INTRODUCTION Alzheimer’s disease (AD) pathology is defined by β-amyloid (Aβ) plaques and neurofibrillary tau, but Lewy bodies (LBs; 𝛼-synuclein aggregates) are a common co-pathology for which effective biomarkers are needed. METHODS A validated...
by Clinical Neuropsychologist Online | Tuesday, May 21, 2024 | Neuroscience
Nature Neuroscience, Published online: 21 May 2024; doi:10.1038/s41593-024-01642-2Mature myelin has been considered static, though recent evidence indicates it is in fact dynamic. Here, Osso and Hughes review the dynamics of mature myelin, a form of neuroplasticity,...
by Clinical Neuropsychologist Online | Tuesday, May 21, 2024 | Neuroscience
Nature Neuroscience, Published online: 21 May 2024; doi:10.1038/s41593-024-01650-2LINE-1 retrotransposons are a type of mobile DNA element normally repressed in the body. Here the authors show that LINE-1 sequences can jump in mouse parvalbumin interneurons and also...
by Clinical Neuropsychologist Online | Tuesday, May 21, 2024 | Neuroscience
Nature Neuroscience, Published online: 21 May 2024; doi:10.1038/s41593-024-01648-wHow the brain tracks blood glucose dynamics is unclear. Viskaitis et al. show that hypothalamic orexin/hypocretin cells track glucose concentration and rate of change and that their...